彻底改变

• about-face
• about face

例句

1. 这些新措施表明政府的政策彻底改变了。
   These new measures indicate an about-turn in government policy.
2. 这种新药的发现彻底改变了许多疾病的治疗方式。
   The discovery of the new drug has revolutionized the treatment of many diseases.